Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456748 | 0.97 | THRB (0.66) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL8928357 | 0.97 | THRB (0.66) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL19456800 | 0.95 | THRB (0.69) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL17033925 | 0.94 | THRB (0.71) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL13368725 | 0.93 | THRB (0.57) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL17033939 | 0.92 | THRB (0.60) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL19456783 | 0.91 | THRB (0.64) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL19456762 | 0.90 | THRB (0.62) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL19456758 | 0.90 | THRB (0.66) | THRBALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL17033932 | 0.90 | THRB (0.66) | THRBALDH1A1TSHRCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126862-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |
| WO-2015126865-A1 | ADHESIVE BONDING COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |