SCHEMBL8928357

SCHEMBL8928357

C=CC(=O)OCCCCOc1cccc(OCCCCOC(=O)C=C)c1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.66
TSHR P16473 6/20 0.58
ALDH1A1 P00352 6/20 0.58
CYP3A4 P08684 1/20 0.58
HPGD P15428 2/20 0.49
KDM4E B2RXH2 2/20 0.45
TP53 P04637 2/20 0.44
HIF1A Q16665 2/20 0.44
HSD17B10 Q99714 1/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 1/20 0.44
ATM Q13315 1/20 0.44
MAPK1 P28482 1/20 0.43
PLA2G4B P0C869 1/20 0.43
PRSS1 P07477 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033934 0.97 THRB (0.62) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL19456748 0.97 THRB (0.66) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL19456800 0.95 THRB (0.69) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL17033925 0.94 THRB (0.71) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL13368725 0.93 THRB (0.57) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL17033939 0.92 THRB (0.60) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL9633402 0.92 THRB (0.78) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL19456783 0.91 THRB (0.64) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL19456762 0.90 THRB (0.62) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL19456758 0.90 THRB (0.66) THRBTSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017176011-A1 COMPOUND FOR ENCAPSULATING ORGANIC ELECTROLUMINESCENT DEVICE, COMPOSITION, AND ENCAPSULATED DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2017-10-12 WO disclosed
US-5635105-A ANISOTROPIC LAYER HAS NEGATIVE BIREFRINGENCE AND COMPRISES POLYMER HAVING DISCOTIC STRUCTURE FUJI PHOTO FILM CO., LTD. (JP) 1997-06-03 US disclosed