Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17036970 | 0.95 | THRB (0.60) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL17034281 | 0.90 | ALDH1A1 (0.74) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL17036926 | 0.90 | THRB (0.57) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL8549379 | 0.89 | THRB (0.64) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL17036773 | 0.88 | THRB (0.56) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL15910581 | 0.87 | THRB (0.62) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL28121765 | 0.87 | THRB (0.62) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL25123477 | 0.87 | USP2 (0.61) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL21312667 | 0.87 | THRB (0.55) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL7624262 | 0.87 | USP2 (0.61) | THRBALDH1A1TSHRTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126865-A1 | ADHESIVE BONDING COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |
| WO-2015126862-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |