Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17036757 | 0.95 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4ESMN1; SMN2THRB | |
| SCHEMBL10580556 | 0.95 | THRB (0.50) | ALDH1A1LMNAKDM4ESMN1; SMN2THRB | |
| SCHEMBL8363546 | 0.89 | NPSR1 (0.57) | ALDH1A1LMNAKDM4ESMN1; SMN2THRB | |
| SCHEMBL17034305 | 0.89 | ALDH1A1 (0.70) | ALDH1A1LMNAKDM4ESMN1; SMN2THRB | |
| SCHEMBL17036774 | 0.89 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4ESMN1; SMN2THRB | |
| SCHEMBL17036922 | 0.89 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4ESMN1; SMN2THRB | |
| SCHEMBL25123525 | 0.87 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL25796435 | 0.87 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL1938350 | 0.87 | THRB (0.46) | ALDH1A1LMNAKDM4ESMN1; SMN2THRB | |
| SCHEMBL4580084 | 0.86 | GAA (0.58) | ALDH1A1LMNAKDM4ESMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126865-A1 | ADHESIVE BONDING COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |
| WO-2015126862-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |