SCHEMBL17033992

SCHEMBL17033992

Cc1nc2oc3ccccc3c2c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 5/20 0.44
▸ MEN1 O00255 3/20 0.44
▸ KMT2A Q03164 3/20 0.44
▸ LMNA P02545 1/20 0.44
▸ ALDH1A1 P00352 4/20 0.42
▸ HPGD P15428 3/20 0.41
▸ BRD4 O60885 1/20 0.41
▸ BRD2 P25440 1/20 0.41
▸ CDK1 P06493 5/20 0.41
▸ CCNB1 P14635 5/20 0.41
▸ CDK5 Q00535 4/20 0.41
▸ CDK5R1 Q15078 4/20 0.41
▸ CCNE1 P24864 4/20 0.41
▸ CDK2 P24941 4/20 0.41
▸ CCNE2 O96020 2/20 0.41
▸ GSK3B P49841 2/20 0.41
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ HSD17B10 Q99714 2/20 0.39
▸ POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15631661 0.81 CDK1 (0.41) SMN1; SMN2LMNAALDH1A1HPGDCDK1
SCHEMBL18708347 0.78 SMN1; SMN2 (0.55) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL25847833 0.77 ESR1 (0.44) SMN1; SMN2LMNAALDH1A1HPGDCDK1
SCHEMBL17033995 0.77 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL19169219 0.76 SMN1; SMN2 (0.52) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL19169809 0.75 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL21032092 0.75 MEN1 (0.42) MEN1KMT2ALMNAALDH1A1HPGD
SCHEMBL21032078 0.74 ESR1 (0.44) SMN1; SMN2LMNAALDH1A1HPGDCDK1
SCHEMBL21031308 0.74 MEN1 (0.41) MEN1KMT2ALMNAALDH1A1HPGD
SCHEMBL21030665 0.74 MEN1 (0.41) MEN1KMT2ALMNAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150243907-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150243907-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS AZI2, BRPF1, CCNB1 SMN1; SMN2 3068/4885MEN1 1139/4885KMT2A 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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