SCHEMBL17033995

SCHEMBL17033995

Cc1nc2oc3ccccc3c2c(C)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.44
▸ MEN1 O00255 3/20 0.44
▸ KMT2A Q03164 3/20 0.44
▸ LMNA P02545 1/20 0.44
▸ ALDH1A1 P00352 7/20 0.43
▸ HPGD P15428 4/20 0.43
▸ L3MBTL1 Q9Y468 4/20 0.43
▸ HSD17B10 Q99714 3/20 0.43
▸ POLB P06746 2/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ DUSP3 P51452 1/20 0.43
▸ PTPN5 P54829 1/20 0.43
▸ PTPN11 Q06124 1/20 0.43
▸ RAB9A P51151 4/20 0.42
▸ NPC1 O15118 2/20 0.42
▸ KDM4E B2RXH2 6/20 0.41
▸ GAA P10253 2/20 0.41
▸ PSMD14 O00487 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29287096 0.81 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL25847178 0.79 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL18708347 0.77 SMN1; SMN2 (0.55) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL17033992 0.77 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL26194082 0.76 NPC1 (0.40) SMN1; SMN2ALDH1A1L3MBTL1NPC1KDM4E
SCHEMBL17033994 0.75 MAOA (0.45) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL19162424 0.75 SMN1; SMN2 (0.42) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL19169219 0.74 SMN1; SMN2 (0.52) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL20042639 0.74 KMT2A (0.47) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL24816077 0.74 HPGD (0.44) SMN1; SMN2MEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150243907-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150243907-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS AZI2, BRPF1, CCNB1 SMN1; SMN2 3068/4885MEN1 1139/4885KMT2A 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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