Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034355 | 1.00 | ALDH1A1 (0.47) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17034210 | 0.96 | ALDH1A1 (0.50) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17034364 | 0.93 | POLB (0.49) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17034233 | 0.93 | POLB (0.49) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17034358 | 0.91 | POLB (0.53) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17034244 | 0.91 | POLB (0.53) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17034229 | 0.89 | POLB (0.52) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17034353 | 0.89 | POLB (0.52) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17036987 | 0.89 | POLB (0.55) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL17034226 | 0.87 | POLB (0.56) | ALDH1A1POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126666-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |