Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034358 | 1.00 | POLB (0.53) | POLBAPEX1HTTTDP1EPHX2 | |
| SCHEMBL17034362 | 0.97 | POLB (0.56) | POLBAPEX1HTTTDP1HRH3 | |
| SCHEMBL17034226 | 0.97 | POLB (0.56) | POLBAPEX1HTTTDP1HRH3 | |
| SCHEMBL17034233 | 0.96 | POLB (0.49) | POLBAPEX1HTTTDP1HRH3 | |
| SCHEMBL17034364 | 0.96 | POLB (0.49) | POLBAPEX1HTTTDP1HRH3 | |
| SCHEMBL17034353 | 0.92 | POLB (0.52) | POLBAPEX1HTTTDP1HRH3 | |
| SCHEMBL17034229 | 0.92 | POLB (0.52) | POLBAPEX1HTTTDP1HRH3 | |
| SCHEMBL17034355 | 0.91 | ALDH1A1 (0.47) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL17034217 | 0.91 | ALDH1A1 (0.47) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL17034210 | 0.88 | ALDH1A1 (0.50) | POLBAPEX1HTTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126666-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |