Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034215 | 0.99 | TDP1 (0.47) | TDP1POLBAPEX1HTTADRB2 | |
| SCHEMBL17034279 | 0.96 | TDP1 (0.43) | TDP1POLBAPEX1HTTADRB2 | |
| SCHEMBL17034222 | 0.95 | TDP1 (0.44) | TDP1POLBAPEX1HTTADRB2 | |
| SCHEMBL17034274 | 0.92 | ABCB1 (0.41) | TDP1POLBAPEX1HTTADRB2 | |
| SCHEMBL17034214 | 0.91 | ABCB1 (0.42) | TDP1POLBAPEX1HTTADRB2 | |
| SCHEMBL17034362 | 0.89 | POLB (0.56) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL17034226 | 0.89 | POLB (0.56) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL17034244 | 0.86 | POLB (0.53) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL17034358 | 0.86 | POLB (0.53) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL17034354 | 0.85 | THRB (0.39) | TDP1ADRB2ADRB1ADRB3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126666-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |