Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294808 | 0.82 | MAPT (0.38) | ALDH1A1MAPTPKMPPM1BPTPN1 | |
| SCHEMBL9430085 | 0.82 | ALDH1A1 (0.37) | ALDH1A1USP2ALOX15TDP1MAPT | |
| SCHEMBL1490750 | 0.73 | — | — | |
| SCHEMBL7330352 | 0.73 | — | — | |
| SCHEMBL1200456 | 0.73 | ALDH1A1 (0.50) | ALDH1A1USP2ALOX15TDP1MAPT | |
| SCHEMBL11688026 | 0.73 | PPM1B (0.46) | ALDH1A1USP2ALOX15TDP1MAPT | |
| SCHEMBL14514261 | 0.73 | ALDH1A1 (0.50) | ALDH1A1USP2ALOX15TDP1MAPT | |
| SCHEMBL27612602 | 0.72 | MAPT (0.43) | ALDH1A1MAPTPKMPPM1BPTPN1 | |
| SCHEMBL2158524 | 0.72 | USP2 (0.32) | ALDH1A1USP2ALOX15TDP1PKM | |
| SCHEMBL20562897 | 0.71 | PPM1B (0.38) | ALDH1A1USP2ALOX15TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444102-A | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-111433206-A | Compound (I) | 葛兰素史克知识产权开发有限公司 | 2020-07-17 | — | — | CN | disclosed |
| EP-2440530-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | Dow AgroSciences LLC (US) | 2012-04-18 | — | — | EP | disclosed |
| EP-2440526-A1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144380-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010144379-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-16 | — | — | WO | disclosed |
| CN-101370776-A | 5-(arylsulfonyl)-pyrazolopiperidines | ELAN PHARM INC (US) | 2009-02-18 | — | — | CN | disclosed |