SCHEMBL17036313

SCHEMBL17036313

Cc1cc(-c2cccc3c2oc2ccccc23)cc(C)c1N(c1ccccc1)c1cc(C)c2ccc3c(N(c4ccccc4)c4c(C)cc(-c5cccc6c5oc5ccccc56)cc4C)cc(C)c4ccc1c2c43

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 5/20 0.37
GGPS1 O95749 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.33
ATM Q13315 1/20 0.33
PGR P06401 1/20 0.32
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
MAOA P21397 1/20 0.31
TTR P02766 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17036318 0.92 ALOX5 (0.40) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL12206326 0.90 ALOX5 (0.45) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL17036315 0.90 ALOX5 (0.39) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL17036267 0.89 ALOX5 (0.43) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL12206423 0.89 ALOX5 (0.44) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL17036314 0.89 ALOX5 (0.38) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL17036307 0.88 ALOX5 (0.41) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL17036316 0.88 ALOX5 (0.38) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL17036284 0.86 ALOX5 (0.40) ALOX5PRKDCATMPGRPIK3CD
SCHEMBL17036305 0.85 ALOX5 (0.39) ALOX5PRKDCGGPS1PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150243892-A1 Organic Compound, Light-Emitting Element, Display Module, Lighting Module, Light-Emitting Device, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-08-27 US disclosed
US-20150243892-A1 Organic Compound, Light-Emitting Element, Display Module, Lighting Module, Light-Emitting Device, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150243892-A1 Organic Compound, Light-Emitting Element, Display Module, Lighting Module, Light-Emitting Device, Display Device, Electronic Device, and Lighting Device ESR1, EHD1, DDT ALOX5 1269/4885PRKDC 2644/4885GGPS1 2472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.