EHD1

EH domain-containing protein 1 · Q9H4M9 · EHD1 on Sugi Atlas →

191 patent compounds predicted against EHD1, 80 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL24626985 SCHEMBL24626985 0.50 7/20
SCHEMBL19428688 SCHEMBL19428688 0.43 7/20
SCHEMBL19428689 SCHEMBL19428689 0.43 7/20
SCHEMBL19428687 SCHEMBL19428687 0.42 7/20
SCHEMBL24626991 SCHEMBL24626991 0.58 6/20
SCHEMBL24627059 SCHEMBL24627059 0.54 6/20
SCHEMBL24627335 SCHEMBL24627335 0.53 6/20
SCHEMBL22887739 SCHEMBL22887739 0.51 6/20
SCHEMBL19432881 SCHEMBL19432881 0.47 6/20
SCHEMBL25802534 SCHEMBL25802534 0.47 6/20
SCHEMBL15748405 SCHEMBL15748405 0.52 5/20
SCHEMBL24625871 SCHEMBL24625871 0.47 5/20
SCHEMBL24625883 SCHEMBL24625883 0.47 5/20
SCHEMBL24625885 SCHEMBL24625885 0.47 5/20
SCHEMBL29884632 SCHEMBL29884632 0.46 5/20
SCHEMBL31612918 SCHEMBL31612918 0.46 5/20
SCHEMBL19767599 SCHEMBL19767599 0.42 5/20
SCHEMBL19428685 SCHEMBL19428685 0.41 5/20
SCHEMBL26067291 SCHEMBL26067291 0.40 5/20
Prenylagaramide A Prenylagaramide A (SCHEMBL29884762) 0.50 4/20

Clinical trials — most relevant to EHD1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients PHASE4NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
Peptide Vaccine Focusing on Prevention of the Recurrence for Bladder Cancer PHASE2UNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Genetic Analysis of Human Hypertensive End Stage Renal Disease (H-ESRD) nanCOMPLETED
Molecular Studies on Hereditary Haemorrhagic Telangiectasia Families nanRECRUITING
Evaluation of Phenotypic and Genetic Properties in Male Subjects Affected By Hypohidrotic Ectodermal Dysplasia nanCOMPLETED
Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders nanCOMPLETED
Epithelioid Haemangioendothelioma Observational Study nanRECRUITING
HE4 is a Beneficial Biomarker in Endometrial Cancer nanUNKNOWN
Global Profiling of Gene and Protein Expression Associated With Coronary Heart Disease Reversal nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders nanRECRUITING
PCD New Gene Discovery nanCOMPLETED
Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform nanRECRUITING
STXBP1 and SYNGAP1 Related Disorders Natural History Study nanRECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Young Pectus Excavatum Patients and Genetic Defects nanCOMPLETED
Exploiting Epigenome Editing in Kabuki Syndrome: a New Route Towards Gene Therapy for Rare Genetic Disorders nanCOMPLETED
Chronic Obstructive Pulmonary Disease Gene Localization nanCOMPLETED
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm nanCOMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a EHD1 binder may also engage these)

ProteinNameSimilarity
Q9WVK4 1.000 Q9WVK4 →
Q5E9R3 1.000 Q5E9R3 →
Q8R491 1.000 Q8R491 →
Q9NZN3 1.000 Q9NZN3 →
Q9QXY6 1.000 Q9QXY6 →
Q9EQP2 1.000 Q9EQP2 →
Q641Z6 1.000 Q641Z6 →
Q8BH64 1.000 Q8BH64 →
Q5RBP4 1.000 Q5RBP4 →
B3LF48 1.000 B3LF48 →
Q94CF0 0.999 Q94CF0 →
Q9H223 0.998 Q9H223 →
Q9NZN4 0.997 Q9NZN4 →
Q4V8H8 0.996 Q4V8H8 →
Q9Z2Q6 0.995 Q9Z2Q6 →
Q9U6A9 0.994 Q9U6A9 →
O44411 0.993 O44411 →
SEPTIN6 Septin-6 0.993 landscape →
Q5ZMH1 0.993 Q5ZMH1 →
Q9V411 0.992 Q9V411 →
Q6Q137 0.991 Q6Q137 →
Q9R1T4 0.991 Q9R1T4 →
Q08DF4 0.991 Q08DF4 →
Q23670 0.991 Q23670 →
Q6GLZ5 0.991 Q6GLZ5 →
Q95XQ8 0.991 Q95XQ8 →
A2BGU8 0.991 A2BGU8 →
DNM1 Dynamin-1 0.991 landscape →
Q99P77 0.990 Q99P77 →
Q642H3 0.990 Q642H3 →