Valine

Valine

SCHEMBL17036698

CC(C)[C@H](N)C(=O)O.C[C@H](NC(=O)c1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.55
CA1 P00915 4/20 0.55
HTT P42858 1/20 0.49
KDM4C Q9H3R0 1/20 0.46
SLC1A2 P43004 1/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SLC7A5 Q01650 1/20 0.44
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
P2RX7 Q99572 1/20 0.44
GAA P10253 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8338918 0.89 CA2 (0.61) CA2CA1HTTKDM4CKDM4E
SCHEMBL2172294 0.89 CA2 (0.61) CA2CA1HTTKDM4CKDM4E
Valine SCHEMBL17036707 0.86 SLC1A2 (0.61) CA2CA1SLC1A2ALDH1A1KMT2A
Valine SCHEMBL17036694 0.86 SLC1A2 (0.61) CA2CA1SLC1A2ALDH1A1KMT2A
Valine SCHEMBL17036690 0.86 SLC1A2 (0.61) CA2CA1SLC1A2ALDH1A1KMT2A
Valine SCHEMBL17036704 0.85 CA2 (0.55) CA2CA1SLC1A2ALDH1A1LMNA
SCHEMBL11103451 0.80 CA2 (0.71) CA2CA1HTTKDM4CALDH1A1
SCHEMBL11103438 0.80 CA2 (0.71) CA2CA1HTTKDM4CALDH1A1
SCHEMBL17036699 0.80 HTT (0.47) CA2CA1HTTKDM4EALDH1A1
SCHEMBL8805714 0.78 HTT (0.57) CA2CA1HTTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9120722-B1 Optically active valine complex and a method for producing the same Wellman Biosciences Co. Ltd. (CN) 2015-09-01 US disclosed