Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17036705 | 0.86 | ALDH1A1 (0.47) | HTTCA2LMNAMEN1KMT2A | |
| SCHEMBL17036691 | 0.86 | SLC1A2 (0.49) | CA2LMNAKMT2ACA1ALDH1A1 | |
| SCHEMBL17036696 | 0.86 | SLC1A2 (0.49) | CA2LMNAKMT2ACA1ALDH1A1 | |
| SCHEMBL27564141 | 0.81 | HTT (0.56) | HTTTRPA1CA2LMNAMEN1 | |
| Valine SCHEMBL17036698 | 0.80 | CA2 (0.55) | HTTTRPA1CA2LMNAMEN1 | |
| SCHEMBL9464650 | 0.77 | HTT (0.59) | HTTTRPA1LMNAMEN1KMT2A | |
| SCHEMBL9464645 | 0.77 | HTT (0.59) | HTTTRPA1LMNAMEN1KMT2A | |
| SCHEMBL8805714 | 0.76 | HTT (0.57) | HTTTRPA1CA2LMNAMEN1 | |
| SCHEMBL8185351 | 0.75 | HTT (0.65) | HTTTRPA1LMNAMEN1KMT2A | |
| SCHEMBL2172294 | 0.74 | CA2 (0.61) | HTTTRPA1CA2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120722-B1 | Optically active valine complex and a method for producing the same | Wellman Biosciences Co. Ltd. (CN) | 2015-09-01 | — | — | US | disclosed |