Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15999342 | 0.80 | RXRA (0.38) | LRRK2ACACBMAP4K1MAPK14POLB | |
| SCHEMBL12873555 | 0.78 | MAP4K1 (0.39) | LRRK2ACACBMAP4K1 | |
| SCHEMBL4268353 | 0.78 | ACACB (0.39) | LRRK2ACACBMAP4K1MAPK14PIK3CA | |
| SCHEMBL12593659 | 0.78 | EDNRB (0.46) | LRRK2ACACBMAP4K1MAPK14POLB | |
| SCHEMBL29370636 | 0.78 | EDNRB (0.46) | LRRK2ACACBMAP4K1MAPK14POLB | |
| SCHEMBL16143061 | 0.77 | ACACB (0.39) | ACACBPOLBRAB9A | |
| SCHEMBL418747 | 0.77 | — | — | |
| SCHEMBL14880201 | 0.76 | SCN9A (0.46) | LRRK2ACACBMAP4K1POLBCCNT1 | |
| SCHEMBL12701660 | 0.76 | LRRK2 (0.37) | LRRK2ACACBMAP4K1MAPK14POLB | |
| SCHEMBL12701665 | 0.76 | MAPK14 (0.40) | LRRK2ACACBMAP4K1MAPK14POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072861-A | For treating the disubstituted pyrazole class compound of disease | FGH生物科技公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-107337659-A | Compounds as protein kinase modulators | 理森制药股份公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-103702989-B | Novel compounds as modulators of protein kinases | 理森制药股份公司 | 2017-07-07 | — | — | CN | disclosed |
| US-20150239920-A1 | Ether Compounds for Treatment of Complement Mediated Disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239920-A1 | Ether Compounds for Treatment of Complement Mediated Disorders | TFPI, CFD, C9 | LRRK2 1907/4885ACACB 3060/4885MAP4K1 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.