Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243833 | 0.92 | PTPN1 (0.44) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL19066414 | 0.90 | KDM4E (0.43) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL17037226 | 0.88 | ALDH1A1 (0.52) | CA9KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL17037215 | 0.87 | KDM4E (0.45) | CA9KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL17037220 | 0.86 | DHODH (0.49) | CA9KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL17037222 | 0.85 | DHODH (0.42) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17037230 | 0.82 | TSHR (0.41) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL28238622 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL17037213 | 0.82 | HDAC1 (0.39) | ALDH1A1TSHRSMN1; SMN2HPGDLMNA | |
| SCHEMBL4271329 | 0.81 | TSHR (0.40) | KDM4EALDH1A1TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181205-B2 | Method for producing oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150239855-A1 | Method for Producing Oxazole Compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239855-A1 | Method for Producing Oxazole Compound | OXA1L, CYB5R3, CBR3 | CA9 206/4885KDM4E 1373/4885ALDH1A1 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.