SCHEMBL17038429

SCHEMBL17038429

c1cc(-c2ccc(-n3c4ccccc4c4ccc(-n5c6ccccc6c6ccccc65)cc43)cc2)cc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.50
PRKDC P78527 12/20 0.43
GGPS1 O95749 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.39
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
PLA2G2A P14555 1/20 0.37
PLA2G4A P47712 1/20 0.37
ATM Q13315 2/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22173218 0.97 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL24936634 0.95 ALOX5 (0.54) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17038432 0.94 ALOX5 (0.48) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL1687741 0.93 ALOX5 (0.50) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17038433 0.93 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL16904459 0.93 ALOX5 (0.52) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17038409 0.93 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL24811949 0.93 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL26788640 0.92 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL18020822 0.92 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707423-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-07-07 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed
US-20150243894-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-08-27 US disclosed
US-20150243894-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 ALOX5 336/4885PRKDC 4297/4885GGPS1 1495/4885
US-10707423-B2 Organic electroluminescent materials and devices OCIAD1, OXA1L, SLCO2B1 ALOX5 702/4885PRKDC 4699/4885GGPS1 1572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.