SCHEMBL24936634

SCHEMBL24936634

c1cc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.54
GGPS1 O95749 1/20 0.44
PRKDC P78527 12/20 0.43
PTGES2 Q9H7Z7 1/20 0.41
PLA2G2A P14555 2/20 0.40
PLA2G4A P47712 2/20 0.40
ATM Q13315 2/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
PLA2G10 O15496 1/20 0.35
PIK3CD O00329 1/20 0.35
PIK3CB P42338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24811949 0.97 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL1687741 0.95 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL17038429 0.95 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18199547 0.94 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL24810410 0.94 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL12996610 0.94 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18199559 0.94 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL24810817 0.93 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18779542 0.93 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18779502 0.93 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND HTR1D, EHD1, HTR3D ALOX5 2107/4885GGPS1 3835/4885PRKDC 4367/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 ALOX5 3712/4885GGPS1 3506/4885PRKDC 4177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.