SCHEMBL17038536

SCHEMBL17038536

C#CC(F)c1ccccc1OP(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 10/20 0.44
INPP5A Q14642 5/20 0.44
INPP5B P32019 2/20 0.44
SRC P12931 5/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
PDE3A Q14432 1/20 0.44
HSD17B10 Q99714 1/20 0.44
AKT1 P31749 1/20 0.39
ACP3 P15309 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30270559 0.81 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL5574733 0.81 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL18685271 0.78 CA1 (0.35) KDM4EALDH1A1
SCHEMBL18680102 0.77 KDM4E (0.35) KDM4EALDH1A1HPGD
SCHEMBL25058821 0.74 KDM4E (0.47) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL17038148 0.74 KDM4E (0.47) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL29613140 0.74 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL224271 0.74 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCKDM4E
Phosphoric Acid SCHEMBL7921303 0.73 INPPL1 (0.50) INPPL1INPP5AINPP5BSRCKDM4E
Benzene SCHEMBL27478938 0.73 KDM4E (0.53) INPPL1INPP5AINPP5BSRCKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018174-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2024-01-18 US disclosed
US-20240018174-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2024-01-18 US disclosed
US-11780863-B2 Quinone methide analog signal amplification VENTANA MEDICAL SYSTEMS, INC. (US) 2023-10-10 US disclosed
US-11780863-B2 Quinone methide analog signal amplification VENTANA MEDICAL SYSTEMS, INC. (US) 2023-10-10 US disclosed
US-11365210-B2 Quinone methide analog signal amplification VENTANA MEDICAL SYSTEMS, INC. (US) 2022-06-21 US disclosed
EP-3492919-A2 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION Ventana Medical Systems, Inc. (US) 2019-06-05 EP disclosed
US-20190128893-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2019-05-02 US disclosed
US-20190127405-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2019-05-02 US disclosed
US-10168336-B2 Quinone methide analog signal amplification VENTANA MEDICAL SYSTEMS, INC. (US) 2019-01-01 US disclosed
US-20170089911-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MEDICAL SYSTEMS, INC. 2017-03-30 US disclosed
US-20170089911-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MEDICAL SYSTEMS, INC. 2017-03-30 US disclosed
WO-2015124703-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MEDICAL SYSTEMS, INC. (US) 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190128893-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION NQO2, SQOR, MRM1 INPPL1 2299/4885INPP5A 2916/4885INPP5B 3193/4885
US-20190127405-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION NQO2, SQOR, MRM1 INPPL1 2299/4885INPP5A 2916/4885INPP5B 3193/4885
US-11780863-B2 Quinone methide analog signal amplification NQO2, SQOR, MRM1 INPPL1 2299/4885INPP5A 2916/4885INPP5B 3193/4885
US-20240018174-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION NQO2, SQOR, MRM1 INPPL1 2299/4885INPP5A 2916/4885INPP5B 3193/4885
US-20170089911-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION NQO2, SQOR, MRM1 INPPL1 2299/4885INPP5A 2916/4885INPP5B 3193/4885
US-10168336-B2 Quinone methide analog signal amplification NQO2, SQOR, MRM1 INPPL1 2299/4885INPP5A 2916/4885INPP5B 3193/4885
US-11365210-B2 Quinone methide analog signal amplification NQO2, SQOR, MRM1 INPPL1 2299/4885INPP5A 2916/4885INPP5B 3193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.