Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301882 | 0.79 | MAPT (0.50) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL9456971 | 0.78 | MAPT (0.57) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL780699 | 0.74 | ALDH1A1 (0.48) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL13917764 | 0.74 | ALDH1A1 (0.48) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL6360840 | 0.73 | KCNN4 (0.58) | MAPTKMT2AALDH1A1CYP3A4ALOX15 | |
| SCHEMBL6652796 | 0.72 | ALDH1A1 (0.42) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL18106924 | 0.72 | MAPT (0.46) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL791664 | 0.71 | MAPT (0.57) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL13784437 | 0.71 | ALDH1A1 (0.50) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL529444 | 0.71 | PDE2A (0.52) | MAPTMEN1KMT2AKIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123722-A1 | INHIBITORS | BIONOMICS LIMITED (AU) | 2015-08-27 | — | — | WO | disclosed |