Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626180 | 0.88 | TSHR (0.53) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL791664 | 0.79 | MAPT (0.57) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL529444 | 0.78 | PDE2A (0.52) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL13784437 | 0.78 | ALDH1A1 (0.50) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL17039751 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL6003717 | 0.76 | MAPT (0.53) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL3879234 | 0.76 | MAPT (0.53) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL11123925 | 0.76 | MAPT (0.44) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| SCHEMBL8073054 | 0.76 | MAPT (0.44) | MAPTMEN1KMT2AKIF11ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3933817 | 0.76 | PDE2A (0.50) | MAPTMEN1KMT2AKIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192810-A | Method and apparatus for manufacturing dimpled structures from elastic cloth | SORRENTO ENGINEERING CORPORATION (US) | 1993-03-09 | — | — | US | disclosed |
| US-5188879-A | Polyimide foam filled structures | SORRENTO ENGINEERING CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0515838-A1 | Method of impregnating reticulated foam with polyimide foam precursor and products thereof | Irbit Research + Consulting AG (CH) | 1992-12-02 | — | — | EP | disclosed |
| EP-0514623-A2 | Method of making honeycomb uniformly filled with foamed in place polyimide foam | Irbit Research + Consulting AG (CH) | 1992-11-25 | — | — | EP | disclosed |
| US-5135959-A | Method of impregnating reticulated foam with polymide foam and products thereof | SORRENTO ENGINEERING CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0251357-B1 | ENGINEERING THERMOPLASTICS CONTAINING PENDANT BENZOCYCLOBUTENE GROUPS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-07-17 | — | — | EP | disclosed |
| US-4708994-A | CURING, CROSSLINKING; SOLVENT RESISTANCE | SHELL OIL COMPANY (US) | 1987-11-24 | — | — | US | disclosed |