Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 13/20 | 0.58 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17039859 | 0.94 | SIRT5 (0.56) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL17039813 | 0.93 | SIRT2 (0.59) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL17039831 | 0.89 | SIRT5 (0.61) | SIRT2SIRT1SIRT3SIRT5KLK7 | |
| SCHEMBL17039855 | 0.86 | SIRT5 (0.57) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL17750718 | 0.86 | SIRT5 (0.57) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL17750717 | 0.85 | SIRT5 (0.56) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL5308048 | 0.85 | SIRT5 (0.59) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL8244805 | 0.85 | SIRT5 (0.59) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL17040116 | 0.85 | MEN1 (0.56) | SIRT2SIRT1SIRT3 | |
| SCHEMBL17040013 | 0.84 | SIRT2 (0.55) | SIRT2SIRT1SIRT3SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123783-A1 | CATHEPSIN B-TARGETING PROBES | THUNDER BAY REGIONAL RESEARCH INSTITUTE (CA) | 2015-08-27 | — | — | WO | disclosed |