Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 10/20 | 0.53 |
| ▸ | MAOA | P21397 | 7/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.53 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040013 | 0.95 | SIRT2 (0.55) | MEN1LMNAKMT2ACTSKHDAC8 | |
| SCHEMBL15062444 | 0.91 | MEN1 (0.65) | MEN1LMNAKMT2ACTSKKDM1A | |
| SCHEMBL17039814 | 0.85 | SIRT2 (0.58) | SIRT1SIRT2SIRT3 | |
| SCHEMBL17040118 | 0.85 | SIRT2 (0.55) | MEN1LMNAKMT2ACTSKHDAC8 | |
| SCHEMBL17040119 | 0.83 | HDAC8 (0.57) | MEN1LMNAKMT2ACTSKHDAC8 | |
| SCHEMBL17040115 | 0.82 | HDAC8 (0.55) | MEN1LMNAKMT2ACTSKHDAC8 | |
| SCHEMBL18099943 | 0.79 | SIRT2 (0.58) | SIRT1SIRT2SIRT3 | |
| SCHEMBL18099942 | 0.79 | SIRT2 (0.58) | SIRT1SIRT2SIRT3 | |
| SCHEMBL17040117 | 0.79 | HDAC8 (0.52) | MEN1LMNAKMT2ACTSKHDAC8 | |
| SCHEMBL13287011 | 0.79 | CTSL (0.62) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123783-A1 | CATHEPSIN B-TARGETING PROBES | THUNDER BAY REGIONAL RESEARCH INSTITUTE (CA) | 2015-08-27 | — | — | WO | disclosed |