Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040115 | 0.87 | HDAC8 (0.55) | HDAC8CTSKCTSSLTA4HNPC1 | |
| SCHEMBL17040119 | 0.85 | HDAC8 (0.57) | HDAC8CTSKCTSSLTA4HNPC1 | |
| SCHEMBL17040011 | 0.83 | SIRT2 (0.43) | HDAC8CTSKSMN1; SMN2 | |
| SCHEMBL15062444 | 0.81 | MEN1 (0.65) | CTSKMEN1LMNAKMT2A | |
| SCHEMBL17040116 | 0.79 | MEN1 (0.56) | HDAC8CTSKMEN1LMNAKMT2A | |
| SCHEMBL17040118 | 0.76 | SIRT2 (0.55) | HDAC8CTSKCTSSCTSLMEN1 | |
| SCHEMBL17040013 | 0.75 | SIRT2 (0.55) | HDAC8CTSKCTSSCTSLMEN1 | |
| SCHEMBL17040012 | 0.73 | SIRT2 (0.45) | HDAC8CTSK | |
| SCHEMBL3572357 | 0.72 | MAOB (0.57) | PTPN1PTPN6PTPN11RAB9ASMN1; SMN2 | |
| SCHEMBL17040010 | 0.72 | MEN1 (0.45) | HDAC8CTSKMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123783-A1 | CATHEPSIN B-TARGETING PROBES | THUNDER BAY REGIONAL RESEARCH INSTITUTE (CA) | 2015-08-27 | — | — | WO | disclosed |