Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007551 | 0.80 | LMNA (0.52) | LMNACCR1CCR5CCR8MMP2 | |
| SCHEMBL16252845 | 0.74 | CCR1 (0.49) | LMNACCR1CCR5CCR8MMP2 | |
| SCHEMBL251028 | 0.73 | PLAU (0.50) | LMNATSHRKDM4ECYP3A4MAPT | |
| SCHEMBL29358794 | 0.73 | PLAU (0.50) | LMNATSHRKDM4ECYP3A4MAPT | |
| SCHEMBL1341511 | 0.73 | SLC40A1 (0.55) | LMNACCR1CCR5CCR8MMP2 | |
| Phenanthroline SCHEMBL28662342 | 0.73 | CCR1 (0.94) | LMNACCR1CCR5CCR8MMP2 | |
| Phenanthroline SCHEMBL44857 | 0.73 | CCR1 (0.94) | LMNACCR1CCR5CCR8MMP2 | |
| Phenanthroline SCHEMBL30477083 | 0.73 | CCR1 (0.94) | LMNACCR1CCR5CCR8MMP2 | |
| Phenanthroline SCHEMBL28519994 | 0.73 | CCR1 (0.94) | LMNACCR1CCR5CCR8MMP2 | |
| Phenanthroline SCHEMBL27616640 | 0.73 | CCR1 (0.94) | LMNACCR1CCR5CCR8MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897379-A | Process for the synthesis of naphthyridine derivatives and intermediates thereof | 美国安进公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-2440245-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | Novartis AG (CH) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144734-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | NOVARTIS AG (CH) | 2010-12-16 | — | — | WO | disclosed |