Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15451404 | 0.86 | NOD1 (0.54) | NOD1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL15451406 | 0.86 | NOD1 (0.54) | NOD1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL2623713 | 0.86 | NOD1 (0.54) | NOD1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL14478726 | 0.86 | NOD1 (0.54) | NOD1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL14478725 | 0.86 | NOD1 (0.54) | NOD1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL15451421 | 0.86 | NOD1 (0.54) | NOD1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL23872076 | 0.86 | NOD1 (0.46) | NOD1FOLH1RIMKLANAALAD2GNPAT | |
| SCHEMBL20122040 | 0.86 | NOD1 (0.46) | NOD1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL17040507 | 0.85 | NOD1 (0.44) | NOD1FOLH1RIMKLANAALAD2GNPAT | |
| SCHEMBL19034951 | 0.85 | NOD1 (0.58) | NOD1FOLH1RIMKLANAALAD2GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008943-A1 | STABLE GLUCAGON ANALOGUES AND USE FOR TREATMENT OF HYPOGLYCAEMIA | NOVO NORDISK A/S (DK) | 2017-01-12 | — | — | US | disclosed |
| WO-2015124612-A1 | STABLE GLUCAGON ANALOGUES AND USE FOR TREATMENT OF HYPOGLYCAEMIA | NOVO NORDISK A/S (DK) | 2015-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008943-A1 | STABLE GLUCAGON ANALOGUES AND USE FOR TREATMENT OF HYPOGLYCAEMIA | GLP1R, IAPP, GCG | NOD1 476/4885KDM4E 1879/4885MAPT 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.