Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.38 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
| ▸ | GNPAT | O15228 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122048 | 0.88 | NOD1 (0.50) | NOD1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL20122041 | 0.88 | NOD1 (0.50) | NOD1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL17040489 | 0.86 | NOD1 (0.49) | NOD1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL25849917 | 0.85 | NOD1 (0.56) | NOD1FOLH1GNPAT | |
| SCHEMBL29362117 | 0.79 | NOD1 (0.50) | NOD1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL12983544 | 0.79 | NOD1 (0.50) | NOD1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL15451421 | 0.79 | NOD1 (0.54) | NOD1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL18272425 | 0.79 | FOLH1 (0.60) | NOD1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL15451406 | 0.79 | NOD1 (0.54) | NOD1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL18082026 | 0.79 | FOLH1 (0.60) | NOD1ALDH1A1KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963496-B2 | Stable glucagon analogues and use for treatment of hypoglycaemia | NOVO NORDISK A/S (DK) | 2018-05-08 | — | — | US | disclosed |