Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11629080 | 0.98 | TSHR (0.48) | TSHRHPGDMEN1KMT2ASLC9A1 | |
| SCHEMBL7962802 | 0.87 | HTR2C (0.46) | HPGDMEN1KMT2ACCR5MAPT | |
| SCHEMBL11627993 | 0.83 | MEN1 (0.53) | TSHRHPGDMEN1KMT2ASLC9A1 | |
| SCHEMBL17040989 | 0.82 | TSHR (0.48) | TSHRHPGDMEN1KMT2AMAPT | |
| SCHEMBL24508171 | 0.81 | KDM4E (0.53) | TSHRHPGDMEN1KMT2AMAPT | |
| SCHEMBL3911579 | 0.81 | MAPT (0.52) | TSHRHPGDMEN1KMT2AMAPT | |
| SCHEMBL16951643 | 0.81 | TSHR (0.53) | TSHRHPGDMEN1KMT2ASLC9A1 | |
| Hydrochloric Acid SCHEMBL18920731 | 0.79 | MAPT (0.51) | TSHRHPGDMEN1KMT2AMAPT | |
| SCHEMBL11314652 | 0.79 | TSHR (0.51) | TSHRHPGDMEN1KMT2ASLC9A1 | |
| SCHEMBL3385153 | 0.78 | TSHR (0.50) | TSHRHPGDMEN1KMT2ASLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |