Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945720 | 0.88 | TSHR (0.65) | TSHRHPGDGAAMAPTMEN1 | |
| SCHEMBL3385153 | 0.88 | TSHR (0.50) | TSHRHPGDGAAMAPTMEN1 | |
| SCHEMBL11627993 | 0.86 | MEN1 (0.53) | TSHRHPGDGAAMAPTMEN1 | |
| SCHEMBL17040919 | 0.85 | SMN1; SMN2 (0.58) | TSHRHPGDGAAMAPTMEN1 | |
| SCHEMBL4364443 | 0.85 | GAA (0.50) | TSHRHPGDGAAMAPTMEN1 | |
| SCHEMBL1809103 | 0.84 | MRGPRX1 (0.49) | TSHRGAAMAPTMEN1KMT2A | |
| SCHEMBL16951643 | 0.84 | TSHR (0.53) | TSHRHPGDGAAMAPTMEN1 | |
| SCHEMBL17040662 | 0.83 | ALDH1A1 (0.58) | TSHRHPGDGAAMAPTMEN1 | |
| SCHEMBL6953541 | 0.82 | RECQL (0.60) | TSHRGAAMAPTMEN1KMT2A | |
| SCHEMBL4627690 | 0.81 | TDP1 (0.70) | TSHRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251546-A | Process for killing internal helminths using certain 1,1-bis-(2-substituted-3-nitrophenyl)alkane or alkylene derivatives | ICI AUSTRALIA LIMITED (AU) | 1981-02-17 | — | — | US | disclosed |