SCHEMBL170406

SCHEMBL170406

C1=COc2ccccc2C1.[Co].[Mo]

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
OXTR P30559 1/20 0.36
LMNA P02545 2/20 0.33
CRHBP P24387 2/20 0.33
CRHR2 Q13324 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3406846 0.98 MAOA (0.37) MAOAMAOBOXTRLMNACRHBP
SCHEMBL174617 0.98 MAOA (0.39) MAOAMAOBOXTRLMNACRHBP
SCHEMBL39996 0.98 MAOA (0.39) MAOAMAOBOXTRLMNACRHBP
SCHEMBL6862603 0.96 MAOA (0.35) MAOAMAOBOXTRLMNACRHBP
SCHEMBL11041082 0.96 MAOA (0.38) MAOAMAOBOXTRLMNACRHBP
SCHEMBL5670912 0.96 MAOA (0.38) MAOAMAOBOXTRLMNACRHBP
SCHEMBL1943716 0.96 MAOA (0.38) MAOAMAOBOXTRLMNACRHBP
SCHEMBL9500450 0.96 MAOA (0.38) MAOAMAOBOXTRLMNACRHBP
SCHEMBL564316 0.96 MAOA (0.38) MAOAMAOBOXTRLMNACRHBP
SCHEMBL130349 0.96 MAOA (0.38) MAOAMAOBOXTRLMNACRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2292 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3181271-B1 THREE-DIMENSIONAL SHAPED ARTICLE PRODUCTION METHOD, THREE-DIMENSIONAL SHAPED ARTICLE PRODUCTION APPARATUS, AND THREE-DIMENSIONAL SHAPED ARTICLE SEIKO EPSON CORP (JP) 2024-07-17 EP claimed
EP-4161448-B1 UNICOMPARTIMENTAL KNEE PROSTHESIS GRUPPO BIOIMPIANTI S R L (IT) 2024-07-10 EP claimed
CN-221205795-U Novel customized 3D prints anatomic type full wrist joint prosthesis 西南医科大学附属医院 2024-06-25 CN claimed
CN-117679140-A Test mold for magnesium metal bone screw and use method thereof 苏州卓恰医疗科技有限公司 2024-03-12 CN claimed
US-20240041612-A1 TOTAL SPINAL JOINT SYSTEMS WITH MOTION MODERATORS 3SPINE INC (US) 2024-02-08 US claimed
CN-117426907-A Personalized first metacarpal prosthesis 北京市春立正达医疗器械股份有限公司 2024-01-23 CN claimed
CN-117323036-A Cobalt-chromium-molybdenum bracket denture of resin denture and preparation method thereof 深圳新致美精密齿研有限公司 2024-01-02 CN claimed
US-20230380984-A1 TOTAL SPINAL JOINT SYSTEMS WITH DISSIMILAR BEARING MATERIALS 3SPINE INC (US) 2023-11-30 US claimed
US-20230363925-A1 INTERVERTEBRAL SPACER THAT DYNAMICALLY PROMOTES BONE GROWTH SIMPLIFY MEDICAL PTY LTD (AU) 2023-11-16 US claimed
EP-4122427-B1 ENDOPROSTHETIC ROTATING HINGE KNEE ASSEMBLIES AND SUBASSEMBLIES MICROPORT ORTHOPEDICS HOLDINGS INC (US) 2023-11-15 EP claimed
WO-1991018561-A1 FEMORAL STEM PROSTHESIS ELTING, JAMES, J. (US) 1991-12-12 WO claimed
US-4944754-A Coating with crystalline hydroxyapatite VENT-PLANT CORPORATION (US) 1990-07-31 US claimed
US-4908030-A Method of manufacturing synthetic bone coated surgical implants VENT-PLANT CORPORATION, INC. (US) 1990-03-13 US claimed
WO-1988008460-A1 METHOD OF MANUFACTURING SYNTHETIC BONE COATED SURGICAL IMPLANTS VENT-PLANT CORPORATION (US) 1988-11-03 WO claimed
EP-0282161-A1 Artificial spinal disc HEALTH & RESEARCH SERVICES INC. (CA) 1988-09-14 EP claimed
US-4759769-A Artificial spinal disc HEALTH & RESEARCH SERVICES INC. (CA) 1988-07-26 US claimed
US-4550450-A Total shoulder prosthesis system KINNETT JAMES G 1985-11-05 US claimed
EP-0048247-B1 ORTHOPAEDIC IMPLANTS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-07-11 EP claimed
EP-0048247-A1 ORTHOPAEDIC IMPLANTS. NAT RES DEV (GB) 1982-03-31 EP claimed
WO-1981002668-A1 ORTHOPAEDIC IMPLANTS NAT RES DEV (GB) 1981-10-01 WO claimed