SCHEMBL174617

SCHEMBL174617

C1=COc2ccccc2C1.[Co]

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
LMNA P02545 2/20 0.34
CRHBP P24387 2/20 0.34
CRHR2 Q13324 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HTT P42858 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
OXTR P30559 1/20 0.33
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17835339 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL7573753 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL18940665 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL170406 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL130349 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL2426653 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL564316 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL5670912 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL1172586 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2
SCHEMBL5996184 0.98 MAOA (0.38) MAOAMAOBLMNACRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11957812-B2 Silicon nitride implants and coatings CTL MEDICAL CORPORATION (US) 2024-04-16 US claimed
CN-113473942-B Flexible castable abutment for manufacturing denture brackets 阿斯特拉植牙健康技术有限公司 2024-03-15 CN claimed
EP-3610814-B1 IMPROVED HEAT TRANSFER DURING ABLATION PROCEDURES BIOSENSE WEBSTER ISRAEL LTD (IL) 2024-02-07 EP claimed
EP-3648952-B1 SURGICAL IMPLANT AND METHODS OF ADDITIVE MANUFACTURING K2M INC (US) 2024-01-24 EP claimed
EP-3496636-B1 INTERVERTEBRAL DISC REPLACEMENT AGADA MEDICAL LTD (IL) 2023-12-13 EP claimed
WO-2023200869-A1 TOTAL JOINT REPLACEMENT SPINAL IMPLANT SYSTEM 3SPINE, INC. (US) 2023-10-19 WO claimed
EP-3518747-B1 MODULATED ULTRA-SOUND COMPATIBLE ARTIFICIAL CRANIAL PROSTHESIS SAMPATH PRAKASH (US) 2023-09-06 EP claimed
CN-116042025-A Coating composition, preparation method thereof and high-weather-resistance and high-reflection black solar cell backboard comprising coating composition 苏州赛伍应用技术股份有限公司 2023-05-02 CN claimed
EP-3574850-B1 OCCLUSIVE DEVICES COVIDIEN LP (US) 2022-07-06 EP claimed
WO-2022025850-A1 HIP PROSTHESIS SYSTEMS USED IN FEMORAL HEAD AND ACETABULUM BONE DEFORMATIONS ESTAS EKSANTRIK SANAYI VE TICARET ANONIM SIRKETI (TR) 2022-02-03 WO claimed
US-5237548-A Magnetic recording layer sandwiched between opaque substrate and magneto-optic layer structure HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-17 US claimed
US-5194001-A Reinforced dental bridge SALVO CHRISTOPHER A (US) 1993-03-16 US claimed
US-5098296-A Subperiosteal denture supporting fixture implant CULLEN RONALD P (GB) 1992-03-24 US claimed
EP-0228399-B1 MIXED DENTAL IMPLANT BOUKHRIS, Gilles (FR) 1991-03-27 EP claimed
US-4713077-A Method of applying a chin implant, drill guide tool and implant SMALL IRWIN A (US) 1987-12-15 US claimed
EP-0228399-A1 MIXED DENTAL IMPLANT. BOUKHRIS GILLES (FR) 1987-07-15 EP claimed
WO-1987000030-A1 MIXED DENTAL IMPLANT BOUKHRIS GILLES 1987-01-15 WO claimed
EP-0042271-B1 INTERVERTEBRAL DISC PROSTHESIS Kuntz, David J. (CA) 1984-09-05 EP claimed
US-4349921-A Intervertebral disc prosthesis KUNTZ J DAVID 1982-09-21 US claimed
US-4079469-A Elbow joint endoprosthesis WADSWORTH THOMAS GORDON 1978-03-21 US claimed