Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.47 |
| ▸ | PPP5C | P53041 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21987133 | 0.79 | PPM1B (0.50) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL8013452 | 0.79 | PPM1B (0.50) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL17040638 | 0.72 | PPM1B (0.38) | PPM1BPTPN1PPP1CC | |
| Cyclopropane SCHEMBL11192707 | 0.71 | SUCNR1 (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| Cyclohexane SCHEMBL11190361 | 0.71 | SUCNR1 (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL24471567 | 0.69 | PPM1B (0.36) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL30165088 | 0.69 | PPM1B (0.36) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL69736 | 0.69 | PPM1B (0.47) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL16570723 | 0.69 | PPM1B (0.47) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL38319 | 0.68 | LMNA (0.46) | PPM1BPTPN1PPP1CCALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |