Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17043074 | 1.00 | P2RX3 (0.62) | P2RX3TDP1HRH3HTR2AHTR7 | |
| SCHEMBL1306250 | 0.91 | P2RX3 (0.60) | P2RX3KDM4EHSD17B10ADAMTS4ADAMTS5 | |
| SCHEMBL1306254 | 0.91 | P2RX3 (0.60) | P2RX3KDM4EHSD17B10ADAMTS4ADAMTS5 | |
| SCHEMBL17043163 | 0.90 | P2RX3 (0.58) | P2RX3KDM4EHSD17B10ADAMTS4ADAMTS5 | |
| SCHEMBL3815479 | 0.90 | P2RX3 (0.58) | P2RX3KDM4EHSD17B10ADAMTS4ADAMTS5 | |
| SCHEMBL1306515 | 0.89 | P2RX3 (0.63) | P2RX3KDM4EADAMTS4ADAMTS5MAPT | |
| SCHEMBL1306516 | 0.89 | P2RX3 (0.63) | P2RX3KDM4EADAMTS4ADAMTS5MAPT | |
| SCHEMBL1306401 | 0.88 | P2RX3 (0.58) | P2RX3KDM4EL3MBTL1 | |
| SCHEMBL1306404 | 0.88 | P2RX3 (0.58) | P2RX3KDM4EL3MBTL1 | |
| SCHEMBL1307203 | 0.88 | P2RX3 (0.66) | P2RX3KDM4EADAMTS4ADAMTS5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2913322-A2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | Korea Research Institute Of Chemical Technology (KR) | 2015-09-02 | — | — | EP | disclosed |