Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17043091 | 1.00 | P2RX3 (0.44) | P2RX3KDM4EALDH1A1HSD17B10ADAMTS4 | |
| SCHEMBL1308495 | 0.89 | P2RX3 (0.47) | P2RX3KDM4EALDH1A1HSD17B10ADAMTS4 | |
| SCHEMBL1308499 | 0.89 | P2RX3 (0.47) | P2RX3KDM4EALDH1A1HSD17B10ADAMTS4 | |
| SCHEMBL1305790 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL1305792 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL29525119 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL1307152 | 0.85 | P2RX3 (0.43) | P2RX3KDM4EALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1307155 | 0.85 | P2RX3 (0.43) | P2RX3KDM4EALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1306630 | 0.85 | P2RX3 (0.49) | P2RX3KDM4EALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1306633 | 0.85 | P2RX3 (0.49) | P2RX3KDM4EALDH1A1ADAMTS4ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2913322-A2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | Korea Research Institute Of Chemical Technology (KR) | 2015-09-02 | — | — | EP | disclosed |