Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305790 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL1305792 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL1306318 | 0.92 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL1306323 | 0.92 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL1305962 | 0.91 | L3MBTL1 (0.48) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL1305961 | 0.91 | L3MBTL1 (0.48) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL1307540 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL1307537 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL29488470 | 0.86 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 | |
| SCHEMBL17043090 | 0.85 | P2RX3 (0.44) | KDM4EALDH1A1HSD17B10L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114340672-A | Pharmaceutical composition comprising an HDAC inhibitor and an anti-PD 1 antibody or an anti-PD-L1 antibody | 晶体基因技术株式会社 | 2022-04-12 | — | — | CN | claimed |
| CN-112930177-B | Pharmaceutical compositions containing alkylcarbamoyl naphthoyl octenoyl hydroxyamide phosphate, tartrate or combinations thereof and methods of making the same | 晶体基因技术株式会社 | 2024-01-30 | — | — | CN | disclosed |
| CN-114340672-A | Pharmaceutical composition comprising an HDAC inhibitor and an anti-PD 1 antibody or an anti-PD-L1 antibody | 晶体基因技术株式会社 | 2022-04-12 | — | — | CN | disclosed |