Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482745 | 0.81 | FUCA1 (0.46) | FUCA1SIGMAR1GBA1TSHRALDH1A1 | |
| SCHEMBL31325224 | 0.81 | FUCA1 (0.46) | FUCA1SIGMAR1GBA1TSHRALDH1A1 | |
| SCHEMBL14801878 | 0.81 | FUCA1 (0.43) | FUCA1SIGMAR1GBA1TSHRCYP2D6 | |
| SCHEMBL14801877 | 0.81 | FUCA1 (0.43) | FUCA1SIGMAR1GBA1TSHRCYP2D6 | |
| SCHEMBL14801875 | 0.81 | FUCA1 (0.43) | FUCA1SIGMAR1GBA1TSHRCYP2D6 | |
| SCHEMBL8388967 | 0.79 | FUCA1 (0.44) | FUCA1SIGMAR1GBA1ALDH1A1 | |
| SCHEMBL23186699 | 0.79 | GAA (0.49) | FUCA1SIGMAR1TSHRCYP2D6CYP3A4 | |
| SCHEMBL20274522 | 0.78 | SIGMAR1 (0.41) | FUCA1SIGMAR1TSHRCYP2D6CYP3A4 | |
| SCHEMBL16724578 | 0.78 | SIGMAR1 (0.41) | FUCA1SIGMAR1TSHRCYP2D6CYP3A4 | |
| SCHEMBL5465323 | 0.77 | ALDH1A1 (0.44) | FUCA1GBA1TSHRCYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015128334-A9 | 3H-THIENO[3,4]PYRIMIDIN-4-ONEAND PYRROLOPYRIMID-4-ONE AS GRAM-POSITIVE ANTIBACTERIAL AGENTS | LABORATOIRE BIODIM (FR) | 2015-10-15 | — | — | WO | disclosed |
| WO-2015128334-A1 | 3H-THIENO[3,4]PYRIMIDIN-4-ONEAND PYRROLOPYRIMID-4-ONE AS GRAM-POSITIVE ANTIBACTERIAL AGENTS | LABORATOIRE BIODIM (FR) | 2015-09-03 | — | — | WO | disclosed |
| EP-2913333-A1 | 3H-thieno[3,4]pyrimidin-4-one and pyrrolopyrimidone as gram-positive antibacterial agents | LABORATOIRE BIODIM (FR) | 2015-09-02 | — | — | EP | disclosed |