Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15158140 | 0.73 | AHR (0.38) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8040114 | 0.73 | ALDH1A1 (0.40) | PTGS2ALDH1A1LMNAGAAHTT | |
| SCHEMBL13176723 | 0.71 | AHR (0.43) | IKBKBMAP3K14PTGS2MAPTAHR | |
| SCHEMBL1699379 | 0.70 | GPR84 (0.43) | CCNB2CDK1CCNB1CCNB3PTGS2 | |
| SCHEMBL1445955 | 0.69 | TSHR (0.41) | ALDH1A1AHRTP53 | |
| SCHEMBL14616507 | 0.68 | PTGDR2 (0.38) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL14089360 | 0.68 | PTGDR2 (0.38) | NPC1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL8049705 | 0.68 | CYP3A4 (0.33) | — | |
| SCHEMBL30259777 | 0.68 | POLB (0.36) | MAPTALDH1A1GAA | |
| SCHEMBL30006589 | 0.66 | CYP3A4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2623494-B1 | AGENT FOR TREATMENT OF EYE DISEASES | DAITO CHEMIX CORP (JP) | 2015-09-02 | — | — | EP | disclosed |