Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892798 | 0.84 | P2RX7 (0.45) | P2RX7EPHX1CHRNA7DPP4 | |
| SCHEMBL892406 | 0.84 | P2RX7 (0.45) | P2RX7EPHX1CHRNA7DPP4 | |
| SCHEMBL892407 | 0.84 | P2RX7 (0.45) | P2RX7EPHX1CHRNA7DPP4 | |
| SCHEMBL25297559 | 0.79 | P2RX7 (0.47) | P2RX7EPHX1CHRNA7 | |
| SCHEMBL15909256 | 0.79 | P2RX7 (0.47) | P2RX7EPHX1CHRNA7 | |
| SCHEMBL25297558 | 0.79 | P2RX7 (0.47) | P2RX7EPHX1CHRNA7 | |
| SCHEMBL892531 | 0.79 | TGFBR1 (0.46) | P2RX7TGFBR1CHRNA7 | |
| SCHEMBL892867 | 0.79 | TGFBR1 (0.46) | P2RX7TGFBR1CHRNA7 | |
| SCHEMBL892532 | 0.79 | TGFBR1 (0.46) | P2RX7TGFBR1CHRNA7 | |
| SCHEMBL31036976 | 0.75 | P2RX7 (0.44) | P2RX7EPHX1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803252-A | Indole amide derivatives and related compounds for use in the treatment of neurodegenerative diseases | UNIV LEUVEN KATH | 2012-11-28 | — | — | CN | disclosed |
| EP-2440550-A1 | INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-04-18 | — | — | EP | disclosed |