Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204311 | 0.85 | MCL1 (1.00) | MCL1BCL2 | |
| SCHEMBL17044260 | 0.84 | MCL1 (0.56) | MCL1BCL2 | |
| SCHEMBL2202702 | 0.80 | MCL1 (0.78) | MCL1BCL2 | |
| SCHEMBL17044286 | 0.78 | MCL1 (0.74) | MCL1BCL2 | |
| SCHEMBL15623504 | 0.77 | MCL1 (1.00) | MCL1 | |
| SCHEMBL17044347 | 0.76 | MCL1 (0.71) | MCL1BCL2 | |
| SCHEMBL22692780 | 0.75 | MCL1 (0.69) | MCL1 | |
| SCHEMBL15622617 | 0.73 | MCL1 (1.00) | MCL1BCL2 | |
| SCHEMBL17044250 | 0.73 | MCL1 (0.54) | MCL1BCL2 | |
| SCHEMBL17044346 | 0.72 | MCL1 (0.50) | MCL1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134685-B1 | 7-NONSUBSTITUTED INDOLE DERIVATIVES AS MCL-1 INHIBITORS | ABBVIE INC (US) | 2015-09-02 | — | — | EP | claimed |