Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17044494 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| Hydrochloric Acid SCHEMBL5703016 | 0.99 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| Hydrochloric Acid SCHEMBL5703020 | 0.99 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| SCHEMBL24211909 | 0.88 | ALDH1A1 (0.63) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| SCHEMBL13673610 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| SCHEMBL13673608 | 0.85 | MAPT (0.47) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| SCHEMBL13673609 | 0.85 | MAPT (0.47) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| SCHEMBL7747080 | 0.84 | SMN1; SMN2 (0.64) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| SCHEMBL7747076 | 0.84 | SMN1; SMN2 (0.64) | KDM4EALDH1A1KMT2AMMP9MEN1 | |
| SCHEMBL17044404 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMMP9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246140-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND WAKEFULNESS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246140-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND WAKEFULNESS | HCRTR2, HCRTR1, NPSR1 | KDM4E 1568/4885ALDH1A1 4570/4885KMT2A 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.