Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 2/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747080 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTCYP1A2MMP9MPO | |
| SCHEMBL24211909 | 0.90 | ALDH1A1 (0.63) | SMN1; SMN2MAPTMMP9GAAALDH1A1 | |
| SCHEMBL12766462 | 0.89 | MMP9 (0.75) | SMN1; SMN2MAPTMMP9MPOGAA | |
| SCHEMBL24211805 | 0.89 | MMP9 (0.75) | SMN1; SMN2MAPTMMP9MPOGAA | |
| SCHEMBL19449697 | 0.88 | MAPT (0.64) | SMN1; SMN2MAPTCYP1A2MMP9MPO | |
| Hydrochloric Acid SCHEMBL17560998 | 0.87 | MAPT (0.62) | SMN1; SMN2MAPTCYP1A2MMP9MPO | |
| SCHEMBL24211803 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTCYP1A2MMP9MPO | |
| SCHEMBL28330693 | 0.86 | MMP9 (0.80) | SMN1; SMN2MAPTCYP1A2MMP9MPO | |
| SCHEMBL23996059 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTCYP1A2MMP9MPO | |
| SCHEMBL17044495 | 0.84 | KDM4E (0.51) | SMN1; SMN2MAPTMMP9ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |
| US-20220015367-A1 | SELF-ASSEMBLED ACTIVE AGENTS | METHODS PRODUCTS PBC | 2022-01-20 | — | — | US | disclosed |
| US-11166464-B2 | Self-assembled active agents | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2021-11-09 | — | — | US | disclosed |
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166464-B2 | Self-assembled active agents | PCNA, POLM, MUS81 | SMN1; SMN2 4332/4885MAPT 4350/4885CYP1A2 3390/4885 |
| US-20220015367-A1 | SELF-ASSEMBLED ACTIVE AGENTS | PCNA, POLM, MUS81 | SMN1; SMN2 4332/4885MAPT 4350/4885CYP1A2 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.