SCHEMBL17044616

SCHEMBL17044616

CCCCCCCCCCCCCCCCCC(=O)[C@]1(O)CC[C@]2(C)[C@H]3CC=C4[C@@H]5CC(C)(C)CC[C@]5(C(=O)O)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 14/20 0.60
PTPN2 P17706 9/20 0.60
ACP1 P24666 3/20 0.60
AKR1B10 O60218 3/20 0.59
GPBAR1 Q8TDU6 3/20 0.59
POLB P06746 3/20 0.59
F3 P13726 3/20 0.59
PSMB11 A5LHX3 2/20 0.59
PSMA7 O14818 2/20 0.59
PLA2G1B P04054 2/20 0.59
PTPRC P08575 2/20 0.59
PTPRF P10586 2/20 0.59
PSMB1 P20618 2/20 0.59
CES1 P23141 2/20 0.59
PSMA1 P25786 2/20 0.59
PSMA2 P25787 2/20 0.59
PSMA3 P25788 2/20 0.59
PSMA4 P25789 2/20 0.59
PSMB8 P28062 2/20 0.59
PSMB9 P28065 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7693463 0.91 PTPN1 (0.59) PTPN1
SCHEMBL17044578 0.85 PTPN1 (0.61) PTPN1PTPN2ACP1AKR1B10GPBAR1
SCHEMBL381229 0.85 PTPN1 (0.69) PTPN1PTPN2ACP1AKR1B10GPBAR1
SCHEMBL2586364 0.82 PTPN1 (0.73) PTPN1PTPN2ACP1AKR1B10GPBAR1
SCHEMBL5799296 0.82 PTPN1 (0.73) PTPN1PTPN2ACP1AKR1B10GPBAR1
SCHEMBL15687736 0.82 PTPN1 (0.68) PTPN1PTPN2ACP1AKR1B10GPBAR1
SCHEMBL15715893 0.81 CETP (0.89) PTPN1PTPN2ACP1PTPN6USP2
SCHEMBL8464067 0.81 CETP (0.89) PTPN1PTPN2ACP1PTPN6USP2
Olean-12-Ene-28-Carboxy-3Beta-Octadecanoate SCHEMBL15715880 0.81 CETP (0.89) PTPN1PTPN2ACP1PTPN6USP2
SCHEMBL15715895 0.79 PTPN1 (0.89) PTPN1PTPN2ACP1AKR1B10GPBAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150246058-A1 COMPOSITION FOR PREVENTING HAIR LOSS AND ACCELERATING HAIR GROWTH RNS CO., LTD. (KR) 2015-09-03 US claimed
CN-104220077-A Composition for preventing hair loss and accelerating hair growth RNS CO LTD 2014-12-17 CN claimed
US-20150246058-A1 COMPOSITION FOR PREVENTING HAIR LOSS AND ACCELERATING HAIR GROWTH RNS CO., LTD. (KR) 2015-09-03 US disclosed
CN-104220077-A Composition for preventing hair loss and accelerating hair growth RNS CO LTD 2014-12-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246058-A1 COMPOSITION FOR PREVENTING HAIR LOSS AND ACCELERATING HAIR GROWTH FGF1, HSD17B7, CYC1 PTPN1 4311/4885PTPN2 4480/4885ACP1 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.