SCHEMBL1704486

SCHEMBL1704486

CCC(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.61
PGR P06401 1/20 0.55
ADRA2A P08913 1/20 0.55
ADRA2B P18089 1/20 0.55
HTR2A P28223 1/20 0.55
HRH1 P35367 1/20 0.55
KCNH2 Q12809 1/20 0.55
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
HSD17B10 Q99714 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CTNNB1 P35222 1/20 0.49
CES1 P23141 4/20 0.48
CES2 O00748 3/20 0.48
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
MAPK1 P28482 2/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442090 0.93 MDM2 (0.59) MDM2PGRADRA2AADRA2BHTR2A
Fluoride SCHEMBL28046161 0.91 MDM2 (0.57) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL3163300 0.90 MDM2 (0.55) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL8882147 0.90 MDM2 (0.55) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL11876338 0.88 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL4871565 0.88 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL4871573 0.88 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL5706319 0.88 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL4871582 0.88 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL17433635 0.86 MDM2 (0.52) MDM2PGRADRA2AADRA2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1649900-B1 Light screening composition comprising a derivative of dibenzoylmethane, a bis-resorcinyl triazine and a compound capable of accepting energy of the excited triplet state of dibenzoylmethane; process for photostabilisation OREAL (FR) 2012-04-18 EP claimed
CN-1921895-A Superabsorbent polymers comprising direct covalent bonds between polymer chain segments and methods of making them PROCTER & GAMBLE (US) 2007-02-28 CN claimed
CN-107722148-A Solid polyaluminoxane composition, catalyst for olefin polymerization, and method for producing olefin polymer 三井化学株式会社 2018-02-23 CN disclosed
CN-107722146-A Method for producing solid polyaluminoxane composition 三井化学株式会社 2018-02-23 CN disclosed
CN-104968668-B Solid polyaluminoxane composition, catalyst for olefin polymerization, method for producing olefin polymer, and method for producing solid polyaluminoxane composition 三井化学株式会社 2017-11-17 CN disclosed
CN-103265420-B A kind of preparation method of aromatic diketone compound WENZHOU UNIVERSITY (CN) 2015-09-02 CN disclosed
CN-101248128-B Coordination polymeric triethanolamine perchloric acid (triflato) metal inner complexes as additives for synthetic polymers CATENA ADDITIVES GMBH & CO KG 2012-05-09 CN disclosed
CN-101248128-A Coordination polymeric triethanolamine perchloric acid (triflato) metal inner complexes as additives for synthetic polymers CATENA ADDITIVES GMBH & CO KG (DE) 2008-08-20 CN disclosed
CN-101076358-A Surface cross-linked superabsorbent polymer particles and methods of making them PROCTER & GAMBLE (US) 2007-11-21 CN disclosed
CN-1921895-A Superabsorbent polymers comprising direct covalent bonds between polymer chain segments and methods of making them PROCTER & GAMBLE (US) 2007-02-28 CN disclosed
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed
US-5420224-A Films and fibers with benzoxazole groups THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1995-05-30 US disclosed
US-5354836-A Polyarylene ether ketone, where at least one ring of the aromatic ketone unit is a thiophene ring THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1994-10-11 US disclosed
US-5266677-A Aromatic polyamides UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1993-11-30 US disclosed
US-4017298-A 1,2,4-Trialkyl-3,5-diphenylpyrazolium salts as herbicides AMERICAN CYANAMID COMPANY (US) 1977-04-12 US disclosed
US-3963741-A 4-Alkyl-1,2-dimethyl-3,5-diphenylpyrazolium salts and derivatives thereof as fungicidal agents AMERICAN CYANAMID COMPANY (US) 1976-06-15 US disclosed
US-3958001-A 4-Alkyl-1,2-dimethyl-3,5-diphenylpyrazolium salts and derivatives thereof as fungicidal agents AMERICAN CYANAMID COMPANY (US) 1976-05-18 US disclosed