SCHEMBL442090

SCHEMBL442090

CCC(C(=O)O)C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.59
PGR P06401 1/20 0.53
ADRA2A P08913 1/20 0.53
ADRA2B P18089 1/20 0.53
HTR2A P28223 1/20 0.53
HRH1 P35367 1/20 0.53
KCNH2 Q12809 1/20 0.53
LMNA P02545 2/20 0.49
HSD17B10 Q99714 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CTNNB1 P35222 1/20 0.47
CES2 O00748 3/20 0.47
CES1 P23141 3/20 0.47
KMT2A Q03164 2/20 0.46
RAB9A P51151 2/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28046161 0.98 MDM2 (0.57) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL1704486 0.93 MDM2 (0.61) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL3163300 0.88 MDM2 (0.55) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL8882147 0.88 MDM2 (0.55) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL21066787 0.86 MDM2 (0.46) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL21066783 0.86 MDM2 (0.46) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL5706319 0.86 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL4871573 0.86 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL4871582 0.86 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A
SCHEMBL4871565 0.86 MDM2 (0.53) MDM2PGRADRA2AADRA2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117758066-A Method for producing low-lead low-iron antimonic oxide powder by smelting antimony ore 广西万仕智稀贵金属科技有限公司 2024-03-26 CN claimed
EP-3823774-B1 SIZING COMPOSITION FOR CASTING MOULDS FOR METAL CASTING, USE THEREOF, AND CASTING MOULDS PROVIDED WITH THE SIZING COMPOSITION ASK CHEMICALS GMBH (DE) 2022-06-08 EP claimed
EP-3823774-A1 SIZING COMPOSITION FOR CASTING MOULDS FOR METAL CASTING, USE THEREOF, AND CASTING MOULDS PROVIDED WITH THE SIZING COMPOSITION ASK Chemicals GmbH (DE) 2021-05-26 EP claimed
EP-3294357-B1 BONE REPLACEMENT MATERIALS, METHOD FOR PRODUCING A BONE REPLACEMENT MATERIAL AND MEDICAL KITS FOR THE TREATMENT OF BONE DEFECTS AESCULAP AG (DE) 2021-03-17 EP claimed
EP-3737707-A1 PHENOLIC RESIN BINDER WITH REDUCED FORMADEHYDE CONTENT ASK Chemicals GmbH (DE) 2020-11-18 EP claimed
US-10724008-B2 Ketoreductases C-LECTA GMBH (DE) 2020-07-28 US claimed
CN-111004292-A Gentamicin derivative and preparation method thereof 卓和药业集团有限公司 2020-04-14 CN claimed
CN-111004291-A Etimicin derivative and synthetic method thereof 卓和药业集团有限公司 2020-04-14 CN claimed
CN-110845554-A Synthesis method of etimicin sulfate 卓和药业集团有限公司 2020-02-28 CN claimed
US-10093905-B2 Ketoreductases C-LECTA GMBH (DE) 2018-10-09 US claimed
EP-1135363-B1 PROCESS FOR THE PREPARATION OF SYMMETRICAL DIACYLHYDRAZINES GREAT LAKES CHEMICAL EUROP (CH) 2003-09-24 EP claimed
EP-0852024-B1 BLACK-AND-WHITE PHOTOTHERMOGRAPHIC AND THERMOGRAPHIC ELEMENTS COMPRISING HYDROGEN ATOM DONOR COMPOUNDS AS CONTRAST ENHANCERS EASTMAN KODAK CO (US) 2002-11-06 EP claimed
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
CN-1076171-C Nondigestible fat compositions containing diversely esterified polyol polyesters for passive oil loss control PROCTER & GAMBLE (US) 2001-12-19 CN claimed
US-5441766-A Employing as precursor copper beta-ketoester alone or with Lewis base ligand in presence or absence of hydrogen KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1995-08-15 US claimed
CN-1090133-A The polyol polyester that contains the difference esterification can not digestion type fat combination with the control passive oil loss PROCTER & GAMBLE (US) 1994-08-03 CN claimed
EP-0340909-B1 PROCESS FOR THE PRODUCTION OF HYDROGEN CYANIDE BY THE VAPOUR PHASE CATALYTIC AMMOXIDATION OF METHANOL NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1993-07-21 EP claimed
US-5158787-A Vapor phase catalytic ammoxidation of methanol NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1992-10-27 US claimed
EP-0045976-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montedison S.p.A. (IT) 1989-11-23 EP claimed
EP-0340909-A1 Process for the production of hydrogen cyanide by the vapour phase catalytic ammoxidation of methanol NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1989-11-08 EP claimed