SCHEMBL17045239

SCHEMBL17045239

CNC(=O)OC[C@@H](N)Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.45
DPP7 Q9UHL4 1/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MMP2 P08253 2/20 0.43
LMNA P02545 1/20 0.43
ANPEP P15144 1/20 0.42
ERAP2 Q6P179 1/20 0.42
ERAP1 Q9NZ08 1/20 0.42
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
DPP8 Q6V1X1 1/20 0.41
DPP9 Q86TI2 1/20 0.41
GAA P10253 1/20 0.41
IDO1 P14902 2/20 0.41
ADRB2 P07550 2/20 0.41
ADRB1 P08588 2/20 0.41
ADRB3 P13945 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17045243 1.00 DPP4 (0.45) DPP4DPP7MEN1KMT2AMMP2
SCHEMBL17045237 1.00 DPP4 (0.45) DPP4DPP7MEN1KMT2AMMP2
SCHEMBL17059058 0.86 DPP4 (0.44) DPP4DPP7MEN1KMT2AMMP2
SCHEMBL30175802 0.85 DPP4 (0.43) DPP4DPP7MEN1KMT2AMMP2
SCHEMBL30175759 0.85 DPP4 (0.43) DPP4DPP7MEN1KMT2AMMP2
SCHEMBL11947641 0.83 DPP4 (0.48) DPP4DPP7MEN1KMT2AMMP2
Hydrochloric Acid SCHEMBL7464122 0.82 DPP4 (0.47) DPP4DPP7MEN1KMT2AMMP2
SCHEMBL11947639 0.82 ATM (0.41) MEN1KMT2AMMP2ANPEPNPC1
SCHEMBL17045267 0.82 ATM (0.41) MEN1KMT2AMMP2ANPEPNPC1
SCHEMBL17045270 0.82 ATM (0.41) MEN1KMT2AMMP2ANPEPNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US disclosed
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS., LTD. 2021-04-22 US disclosed
US-10888542-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-01-12 US disclosed
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2020-02-13 US disclosed
EP-3110792-B1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO LTD (KR) 2019-09-04 EP disclosed
US-20190247356-A1 Aminocarbonylcarbamate Compounds SK BIOPHARMACEUTICALS CO., LTD. 2019-08-15 US disclosed
US-10314808-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2019-06-11 US disclosed
US-20180085337-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2018-03-29 US disclosed
US-9833432-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2017-12-05 US disclosed
EP-3110792-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK Biopharmaceuticals Co., Ltd. (KR) 2017-01-04 EP disclosed
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. 2016-10-20 US disclosed
US-9403761-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2016-08-02 US disclosed
WO-2015130121-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 WO disclosed
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190247356-A1 Aminocarbonylcarbamate Compounds SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885
US-10888542-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885
US-20180085337-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885
US-10314808-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885MEN1 3064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.