SCHEMBL30175802

SCHEMBL30175802

NC(=O)CNC(=O)OCC(N)Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.43
DPP7 Q9UHL4 1/20 0.43
DPP8 Q6V1X1 1/20 0.42
DPP9 Q86TI2 1/20 0.42
MMP2 P08253 2/20 0.42
LMNA P02545 1/20 0.41
ANPEP P15144 1/20 0.41
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
MAPT P10636 3/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
IDO1 P14902 2/20 0.39
ALDH1A1 P00352 2/20 0.39
LOXL2 Q9Y4K0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30175759 1.00 DPP4 (0.43) DPP4DPP7DPP8DPP9MMP2
SCHEMBL11947641 0.87 DPP4 (0.48) DPP4DPP7MMP2LMNAANPEP
SCHEMBL17059058 0.86 DPP4 (0.44) DPP4DPP7DPP8DPP9MMP2
Hydrochloric Acid SCHEMBL7464122 0.85 DPP4 (0.47) DPP4DPP7MMP2LMNAANPEP
SCHEMBL17045237 0.85 DPP4 (0.45) DPP4DPP7DPP8DPP9MMP2
SCHEMBL17045243 0.85 DPP4 (0.45) DPP4DPP7DPP8DPP9MMP2
SCHEMBL17045239 0.85 DPP4 (0.45) DPP4DPP7DPP8DPP9MMP2
SCHEMBL11069589 0.83 IDO1 (0.51) DPP8DPP9MAPTIDO1ALDH1A1
SCHEMBL30175820 0.82 SLC6A4 (0.49) DPP4DPP7LMNAMEN1KMT2A
SCHEMBL30175783 0.82 ATM (0.39) DPP4MMP2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US claimed
US-20240358668-A1 METHODS AND COMPISITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCUALR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE WILMINGTON TRUST, NATIONAL ASSOCIATION 2024-10-31 US disclosed
EP-4395763-A1 METHODS AND COMPOSITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCULAR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE AXSOME THERAPEUTICS (US) 2024-07-10 EP disclosed
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US disclosed
WO-2023034944-A1 METHODS AND COMPOSITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCULAR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE AXSOME THERAPEUTICS (US) 2023-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358668-A1 METHODS AND COMPISITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCUALR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE FABP3, CPB2, TNNI3 DPP4 157/4885DPP7 101/4885DPP8 122/4885
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.