SCHEMBL17045259

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6933686	1.00	SIGMAR1 (0.59)	SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4
	SCHEMBL17045222	0.78	SIGMAR1 (0.50)	SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4
	SCHEMBL17045227	0.78	SIGMAR1 (0.50)	SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4
	SCHEMBL18995780	0.77	SIGMAR1 (0.59)	SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4
	SCHEMBL8837452	0.77	NPC1 (0.56)	SIGMAR1TAAR1SLC18A2CYP3A4
	SCHEMBL8694702	0.77	HTR2A (0.56)	SIGMAR1SLC6A2SLC6A4SLC6A3CYP2A6
	SCHEMBL1697045	0.76	SIGMAR1 (0.64)	SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4
	SCHEMBL10513016	0.76	SIGMAR1 (0.59)	SIGMAR1TAAR1SLC18A2EPHX1KDM4E
	SCHEMBL6956150	0.76	EPHX1 (0.43)	SIGMAR1TAAR1SLC18A2SLC6A2SLC6A4
	Methamphetamine SCHEMBL15094315	0.74	SIGMAR1 (1.00)	SIGMAR1TAAR1SLC18A2SLC6A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.