SCHEMBL17045261

SCHEMBL17045261

NC(=O)N(CC(N)Cc1ccccc1F)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 16/20 0.43
DPP7 Q9UHL4 3/20 0.43
DPP8 Q6V1X1 2/20 0.41
DPP9 Q86TI2 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21314303 0.83 PPARG (0.41) DPP4DPP8DPP9PPARGPPARA
SCHEMBL21314307 0.83 PPARG (0.41) DPP4DPP8DPP9PPARGPPARA
SCHEMBL21243716 0.80 EPHX1 (0.52)
SCHEMBL21243718 0.80 EPHX1 (0.52)
SCHEMBL4350725 0.78 DPP4 (0.42) DPP4DPP7DPP8DPP9ALDH1A1
SCHEMBL4350733 0.78 DPP4 (0.42) DPP4DPP7DPP8DPP9ALDH1A1
Carbamic Acid SCHEMBL28108559 0.77 DPP4 (0.48) DPP4DPP7DPP8DPP9ALDH1A1
SCHEMBL978947 0.77 DPP4 (0.57) DPP4DPP7DPP8DPP9
SCHEMBL978945 0.77 DPP4 (0.57) DPP4DPP7DPP8DPP9
SCHEMBL288309 0.77 DPP4 (0.57) DPP4DPP7DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3110792-B1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO LTD (KR) 2019-09-04 EP claimed
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US disclosed
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS., LTD. 2021-04-22 US disclosed
US-10888542-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-01-12 US disclosed
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2020-02-13 US disclosed
EP-3110792-B1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO LTD (KR) 2019-09-04 EP disclosed
US-20190247356-A1 Aminocarbonylcarbamate Compounds SK BIOPHARMACEUTICALS CO., LTD. 2019-08-15 US disclosed
US-10314808-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2019-06-11 US disclosed
US-20180085337-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2018-03-29 US disclosed
US-9833432-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2017-12-05 US disclosed
EP-3110792-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK Biopharmaceuticals Co., Ltd. (KR) 2017-01-04 EP disclosed
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. 2016-10-20 US disclosed
US-9403761-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2016-08-02 US disclosed
US-20160168567-A1 UNA SINGLE STRANDED OLIGOMERS FOR THERAPEUTICS MARINA BIOTECH, INC. 2016-06-16 US disclosed
WO-2015130121-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 WO disclosed
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190247356-A1 Aminocarbonylcarbamate Compounds SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885
US-10888542-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885
US-20180085337-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885
US-10314808-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 DPP4 1476/4885DPP7 1837/4885DPP8 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.