SCHEMBL21243718

SCHEMBL21243718

NC(=O)N(CC(N)Cc1ccccc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.52
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
SLC7A5 Q01650 1/20 0.49
MMP2 P08253 3/20 0.46
LAP3 P28838 3/20 0.46
ANPEP P15144 2/20 0.46
SLC1A3 P43003 2/20 0.45
SLC1A2 P43004 2/20 0.45
SLC1A1 P43005 2/20 0.45
CYP1A2 P05177 1/20 0.43
SLC15A1 P46059 1/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42
LTA4H P09960 1/20 0.41
GPR88 Q9GZN0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21243716 1.00 EPHX1 (0.52) EPHX1ALPIPKMPTGS1XIAP
SCHEMBL17045258 0.86 SLC6A4 (0.53) ANPEP
SCHEMBL21314254 0.84 PNMT (0.49) ANPEP
SCHEMBL17045246 0.82 EPHX1 (0.41) EPHX1ANPEP
SCHEMBL17045266 0.81 DPP4 (0.46) EPHX1MMP2ANPEPCYP1A2
SCHEMBL21314307 0.80 PPARG (0.41) PKM
SCHEMBL21314303 0.80 PPARG (0.41) PKM
SCHEMBL17045261 0.80 DPP4 (0.43)
SCHEMBL21314279 0.80 ALDH1A1 (0.53) EPHX1ALPIPKMPTGS1XIAP
SCHEMBL21314278 0.80 ALDH1A1 (0.53) EPHX1ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3587394-B1 AMINOCARBONYLCARBAMATE COMPOUNDS AND THEIR USE IN THE TREATMENT OF HYPERKINETIC DISORDERS SUCH AS ADHD SK BIOPHARMACEUTICALS CO LTD (KR) 2023-11-01 EP claimed
US-20230255921-A1 COMPOSITION FOR TREATING KCA3.1 CHANNEL-MEDIATED DISEASES COMPRISING PHENYLALKYL CARBAMATE COMPOUND CELLIONBIOMED INC. (KR) 2023-08-17 US claimed
EP-4223291-A1 COMPOSITION FOR TREATING KCA3.1 CHANNEL-MEDIATED DISEASES COMPRISING PHENYLALKYL CARBAMATE COMPOUND Cellionbiomed Inc. (KR) 2023-08-09 EP claimed
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US claimed
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS., LTD. 2021-04-22 US claimed
US-10888542-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-01-12 US claimed
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2020-02-13 US claimed
US-20190247356-A1 Aminocarbonylcarbamate Compounds SK BIOPHARMACEUTICALS CO., LTD. 2019-08-15 US claimed
US-20230255921-A1 COMPOSITION FOR TREATING KCA3.1 CHANNEL-MEDIATED DISEASES COMPRISING PHENYLALKYL CARBAMATE COMPOUND CELLIONBIOMED INC. (KR) 2023-08-17 US disclosed
EP-4223291-A1 COMPOSITION FOR TREATING KCA3.1 CHANNEL-MEDIATED DISEASES COMPRISING PHENYLALKYL CARBAMATE COMPOUND Cellionbiomed Inc. (KR) 2023-08-09 EP disclosed
EP-3110792-B1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO LTD (KR) 2019-09-04 EP disclosed
US-20160168567-A1 UNA SINGLE STRANDED OLIGOMERS FOR THERAPEUTICS MARINA BIOTECH, INC. 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255921-A1 COMPOSITION FOR TREATING KCA3.1 CHANNEL-MEDIATED DISEASES COMPRISING PHENYLALKYL CARBAMATE COMPOUND KCNA3, KCNN3, KCNMA1 EPHX1 1970/4885ALPI 4726/4885PKM 296/4885
US-20190247356-A1 Aminocarbonylcarbamate Compounds SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885ALPI 1778/4885PKM 3184/4885
US-10888542-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885ALPI 1778/4885PKM 3184/4885
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885ALPI 1778/4885PKM 3184/4885
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885ALPI 1778/4885PKM 3184/4885
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 EPHX1 3504/4885ALPI 1778/4885PKM 3184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.