SCHEMBL17045281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17059061	0.85	NR1H4 (0.43)	EPHX2NR1H4EPHX1ALDH1A1ACACB
	SCHEMBL21221627	0.83	EPHX1 (0.50)	EPHX2NR1H4TP53TSHREPHX1
	SCHEMBL21221626	0.83	EPHX1 (0.50)	EPHX2NR1H4TP53TSHREPHX1
	SCHEMBL11947644	0.83	CYP1A2 (0.41)	ALDH1A1LMNA
	SCHEMBL8540131	0.81	SLC7A5 (0.51)	LMNA
	SCHEMBL11947645	0.81	SLC7A5 (0.51)	LMNA
	SCHEMBL11955261	0.80	LDHA (0.54)	EPHX2ALDH1A1LMNAKMT2A
	Carbamic Acid SCHEMBL28108890	0.80	TP53 (0.47)	EPHX2NR1H4TP53TSHREPHX1
	SCHEMBL11947637	0.80	SLC6A4 (0.58)	EPHX2MEN1LMNAKMT2A
	SCHEMBL28571030	0.80	ANPEP (0.46)	EPHX2NR1H4ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.